Neurociencia Cognitiva y Salud Mental
Objetivos del equipo de investigación
En nuestro equipo buscamos llegar a una mejor comprensión acerca de como funcionan problemáticas de la salud mental como la depresión o la ansiedad social, con el fin de que a largo plazo este conocimiento de lugar a mejores tratamientos. En particular, buscamos entender como funcionan estos trastornos en cuanto a la toma de decisiones y al funcionamiento cerebral. Con este fin, trabajamos desarrollando experimentos psicológicos y utilizamos las técnicas de la resonancia magnética funcional (fMRI) y la electroencefalografía (EEG), que permiten explorar el funcionamiento cerebral en humanos.
Aims of the research team
In our team we aim to reach a better understanding of how mental health disorders such as depression or social anxiety work, so that in the long term this knowledge leads to better treatments. In particular, we seek to understand how these disorders work in terms of decision-making and brain function. To this end, we work developing psychological experiments and use techniques such as functional magnetic resonance imaging (fMRI) and electroencephalography (EEG), which allow exploration of brain function in humans.
Publicaciones
2022
Uriarte-Gaspari, L., Acuña, A., Morales, S., Fernández-Theoduloz, G., Paz, V., Pérez, A., & Gradin, V.B. (2022). Who do I want in my team: social avoidance of high qualified partners in depression and social anxiety. Journal of Affective Disorders Report 10.
2021
Cervantes Constantino, F., Garat, S., Nicolaisen-Sobesky, E., Paz, V., Martínez-Montes, E., Kessel, D., Cabana, Á., & Gradin, V. B. (2021). Neural processing of iterated prisoner’s dilemma outcomes indicates next-round choice and speed to reciprocate cooperation. Social Neuroscience, 16(2): 103-120 https://doi.org/10.1080/17470919.2020.1859410
2019
Fernández-Theoduloz, G., Paz, V., Nicolaisen-Sobesky, E., Pérez, A., Buunk, A. P., Cabana, Á., & Gradin, V. B. (2019). Social avoidance in depression: A study using a social decision-making task. Journal of Abnormal Psychology, 128(3), 234–244. https://doi.org/10.1037/abn0000415
2017
Paz, V., Nicolaisen-Sobesky, E., Collado, E., Horta, S., Rey, C., Rivero, M., … Gradin, V. B. (2017). Effect of self-esteem on social interactions during the Ultimatum Game. Psychiatry Research, 252, 247–255. https://doi.org/10.1016/j.psychres.2016.12.063
2016
Gradin, V. B., Pérez, A., MacFarlane, J. A., Cavin, I., Waiter, G., Tone, E. B., … Steele, J. D. (2016). Neural correlates of social exchanges during the Prisoner’s Dilemma game in depression. Psychological Medicine, 46(6). https://doi.org/10.1017/S0033291715002834
2015
Gradin, V. B., Pérez, A., MacFarlane, J. A., Cavin, I., Waiter, G., Engelmann, J., … Steele, J. D. (2015). Abnormal brain responses to social fairness in depression: An fMRI study using the Ultimatum Game. Psychological Medicine, 45(6). https://doi.org/10.1017/S0033291714002347
Johnston, B. A., Tolomeo, S., Gradin, V.B., Christmas, D., Matthews, K., & Douglas Steele, J. (2015). Failure of hippocampal deactivation during loss events in treatment-resistant depression. Brain, 138(9). https://doi.org/10.1093/brain/awv177
2014
Sokunbi, M. O., Gradin, V. B., Waiter, G. D., Cameron, G. G., Ahearn, T. S., Murray, A. D., … Staff, R. T. (2014). Nonlinear complexity analysis of brain fMRI signals in schizophrenia. PLoS ONE, 9(5). https://doi.org/10.1371/journal.pone.0095146
Gradin, V. B., Baldacchino, A., Balfour, D., Matthews, K., & Steele, J. D. (2014). Abnormal brain activity during a reward and loss task in opiate-dependent patients receiving methadone maintenance therapy. Neuropsychopharmacology, 39(4). https://doi.org/10.1038/npp.2013.289
2013
Gradin, V. B., Waiter, G., O’Connor, A., Romaniuk, L., Stickle, C., Matthews, K., … Douglas Steele, J. (2013). Salience network-midbrain dysconnectivity and blunted reward signals in schizophrenia. Psychiatry Research, 211(2), 104–111. https://doi.org/10.1016/j.pscychresns.2012.06.003S0925-4927(12)00127-8 [pii]
2012
Gradin, V. B., Waiter, G., Kumar, P., Stickle, C., Milders, M., Matthews, K., … Steele, J. D. (2012). Abnormal neural responses to social exclusion in schizophrenia. PLoS One, 7(8), e42608. https://doi.org/10.1371/journal.pone.0042608PONE-D-12-14947 [pii]
2011
Gradin, V. B., Kumar, P., Waiter, G., Ahearn, T., Stickle, C., Milders, M., … Steele, J. D. (2011). Expected value and prediction error abnormalities in depression and schizophrenia. Brain, 134(6). https://doi.org/10.1093/brain/awr059
2010
Gradin, V.B., Gountouna, V.-E., Waiter, G., Ahearn, T. S., Brennan, D., Condon, B., … Steele, J. D. (2010). Between- and within-scanner variability in the CaliBrain study n-back cognitive task. Psychiatry Research - Neuroimaging, 184(2). https://doi.org/10.1016/j.pscychresns.2010.08.010
2008
Gradin, V. B., & Pomi, A. (2008). The role of hippocampal atrophy in depression: a neurocomputational approach. J Biol Phys, 34(1–2), 107–120. https://doi.org/10.1007/s10867-008-9099-7
English